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He left Seleucus with a small number of troops to prevent Eumenes from reaching the Mediterranean. His name was given to the empire he and his successors ruled.

After Seleucus’ death in 281 BCE, his sprawling empire was ruled by his descendants. He crossed the Hellespont and met the Romans in battle at Antiochus III’s son and successor, Seleucus IV Philopator (r. 187-175 BCE), continued the efforts to pay off the war debt to the extent that this became his primary focus. He had already prepared this campaign using the numerous gifts presented to him. The chaos of the monarchy at this time is exemplified in the figure of While he was in captivity, his brother, Antiochus VII Sidetes (r. 138-129 BCE), married Cleopatra to gain the throne. The empire had two capitals. The king (emperor) was the supreme power but took counsel from his advisors who passed his decrees to secretaries who then relayed these to regional governors (the satraps). Seleucus participated in the conquest of the Persian empire as one of Alexander’s officers, and in 326 bce he commanded the Macedonian infantry against King Porus of India in battle on the Hydaspes River. Then in the Battle of Ipsus, during the fourth Diadoch war, Antigonus was defeated, Seleucus conquered Syria.In September 281, Ptolemy Keraunos assassinated Seleucus, who was buried in a city he had founded and named for himself. The Seleucid Empire was a Hellenistic state that existed between the 4th and 1st centuries BC. Perhaps Nicanor had not told him that Seleucus now had at least 20,000 soldiers. Antiochus III, even without Hannibal’s guidance, believed he could beat Rome. Debated by Tarn, "The Greeks in Bactria and India", p. 100Hindu Nationalism, A Reader, by Christopher Jeffrelot, Princeton University Press, 2007 Foreign Influence on Ancient India, Krishna Chandra Sagar, Northern Book Centre, 1992, "And Theophrastus says that some contrivances are of wondrous efficacy in such matters [as to make people more amorous].

Alexander the Great's mother After arriving in Egypt, Seleucus sent his friends to Greece to inform his fellow Diadochi Cassander (ruler of Macedon and overlord of Greece) and Lysimachus (ruler of Seleucus had prepared his return to Babylon well.

He was assassinated in 175 BCE and rule passed to Antiochus III’s other son, Antiochus IV Epiphanes (r. 175-164 BCE).